Difficulties of Detection and Diagnosis

نویسنده

  • JON M. AASE
چکیده

U about 20 years ago, the dangers of maternal alcohol consumption to the developing fetus were generally minimized or dismissed. Reports linking maternal alcohol use and fetal growth deficiency emerged from France in the late 1950’s. Then in 1968, Lemoine and colleagues (1968) described growth deficit, mental retardation, and an unusually high rate of birth defects in 127 children born to alco­ holic mothers. In addition, Ulleland (1972) found pre­ and postnatal growth deficiency and developmental abnormalities in 8 of 12 children born to alcoholic mothers. Based in part on these cases, Jones and Smith (1973) introduced the term “fetal alcohol syndrome” (FAS) to describe a pattern of abnormalities found in some children born to alcoholic women. Jones and Smith’s definition was significant because it clearly delineated a clinically recognizable syndrome that was distinct from all other patterns of congenital mal­ formation and that was seen exclusively in the offspring of mothers who drank large amounts1 of alcohol during pregnancy. During the next few years, more than 100 patients with FAS were reported. The earliest descriptions concentrated on the

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تاریخ انتشار 2013